Allergy: Over-eagerness of the immune system

The number of diseases of the allergic type (asthma, hay fever, sun allergy, atopic eczema and food allergies) is constantly increasing. Since 1950, in some industrialized nations we have been observing increase rates of hay fever, asthma and atopic eczema of up to 5 % per year.

And more and more often it happens even to the youngest. Already about 20 % of children under the age of three are suffering from an allergy. 24 % of Germans suffer from an allergy, 41 % of these have hay fever.

A normally responsive immune system fights intruders such as viruses, bacteria, fungi as well as other foreign substances in most cases without leading to disease. Substances identified as harmless are essentially ignored. By contrast, an overzealous immune system reacts to such harmless substances with unreasonable violence – an allergic reaction.

The spectrum of substances causing allergies, the so-called allergens, is very broad. It ranges from plant components (pollen, plant fibres) through foodstuffs (e.g. strawberries, kiwi) to metals (e.g. nickel, copper) and even sunlight.

Allergy treatment – often only symptomatic!

Often these diseases can be treated only symptomatically, e.g. with antihistamines, anti-inflammatory drugs or immunosuppressants.

Consequence:
The clinical symptoms improve in the short term; after the end of therapy there is, however, often overshooting of the disease process, which necessitates long-term therapy and dose increases entailing high incidence of side effects, because the root cause of the allergy was not treated.

Allergy = injured intestinal mucosa

For the successful treatment of allergies it must be kept in mind that the onset of these conditions is almost always correlated to an injured mucosa.<br/>The mucosal membranes must provide a powerful defense against invading pathogens and toxins. With a total surface of about 500 m², they present a vast target. By comparison, the skin has a very small surface of only 1 - 2 m².

Of the mucosa-lined organs, the intestine represents the major contact area of the body with the environment, rather than the skin or the mucosal membrans of the respiratory tract.

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Of the organs lined with mucous membranes, the intestine constitutes the main area of contact of the body with the environment, not the skin or mucous membranes of the respiratory tract.

The intestine with its surface of about 400 m² is not only the largest digestive organ, but also the biggest immune organ. The gut-associated immune system comprises almost 80 % of all immune cells of the human body.

 

Allergy Cause: Food

With the food, not only vital nutrients and energy are supplied to the organism, but also countless foreign substances and pathogens. From this a vital dual role of the intestinal mucosa follows:

  • It must be permeable to nutrients
  • while preventing the ingress of contaminants

This illustrates the importance of an intact intestinal mucosa for the health of the whole body.

Hidden food allergies existing for a long time manifest sooner or later e.g. as hay fever (allergic rhinitis), allergic asthma or atopic dermatitis. This expansion of allergy, begun in the intestine, can occur because all skin and mucosal areas are connected via the mucosa-associated immune system. There is the so-called "allergic march" of the disease.

Therefore, many people with eczema or hay fever show allergic reactions to various foods, too. The reason for these so-called cross-allergies is the similarity of the molecular structure of food allergens and the allergens in the respiratory tract (e.g. pollen) or on the skin (e.g. mites).

Hence, it is clear that a rational treatment of allergies must be accompanied by therapy of the intestinal mucosa and its associated immune system. Thus the causes due to which the disease has arisen can be addressed.

Allergic diseases can be improved via therapy of the mucous membranes with Synerga®!

Please note, however, that this information does not replace a detailed discussion with your doctor. Some information may also cause unnecessary fears. Please talk to your doctor about such concerns. And we explicitly encourage you to ask your doctor your questions, even very personal questions that cannot be answered by this information.

Please read the patient information leaflet carefully. If you have any further questions after reading it, please ask your doctor or pharmacist.