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Sun allergy

Polymorphic light eruption (sun allergy)

For some travellers, holiday fun on the sunny beach is much tarnished. They react with hives, blisters and itching to the excessively bright sun of the South. They suffer from the most common form of dermatosis, the so-called polymorphic light eruption. Here irradiation of sunlight or UV cause the skin lesions described. The best prophylactic treatment is to avoid sun exposure. But for those affected that would mean not being allowed to leave the hotel room!

Light eruption may, however, be caused by so-called phototoxic reactions as well. These are reactions after taking medications (certain antibiotics, rheumatic agents, cardiac drugs, or certain types of contraceptives), which can form free radicals in the skin upon irradiation with sunlight.
In nature there are also substances that can cause phototoxic reactions; most notorious is the Giant Hogweed where often only 1 – 2 days later at the places that had contact with the plant burning pain and skin lesions may occur. Unsightly reddish brown spots remain. Compared to giant hogweed, St. John's Wort oil, which can increase the photosensitivity of the skin, is almost harmless.

In the case of the so-called Majorca acne, the skin reacts only after use of certain cosmetics – fatally including sunscreens – and sun-bathing. This produces small nodules and pustules on the neck, cleavage, upper arms and legs.

Cause of polymorphic light eruption

Skin not accustomed to sunlight will usually react in a hypersensitive manner. A hyperactive immune system tries to fend off an excess of sunlight by completely exaggerated skin reactions.
    
In order to help such a skin, treatment of the immune system is indispensable. Often the reason underlying such excessive reactions is increased permeability of the intestinal mucosa. Here the course is set – incorrectly. By allowing substances to pass which inside the body are classified as hostile, the mucous membrane forces the immune system into an inflammatory reaction. This reaction cannot be controlled as long as the mucous membrane continues to let such substances through.

A rational treatment must be accompanied by therapy of the intestinal mucosa and its associated immune system. Thus the causes due to which the disease has arisen can be addressed.

With Synerga® there is a rational treatment option that has been successfully tested in clinical trials.

Please note, however, that this information does not replace a detailed discussion with your doctor. Some information may also cause unnecessary fears. Please talk to your doctor about such concerns. And we explicitly encourage you to ask your doctor your questions, even very personal questions that cannot be answered by this information.

Please read the patient information leaflet carefully. If you have any further questions after reading it, please ask your doctor or pharmacist.


Laves-Arzneimittel GmbH
Barbarastr. 14 | D-30952 Ronnenberg | Germany
Tel: +49 (0) 511 438 740 | Fax: +49 (0) 511 438 74 44
info@laves-pharma.de | www.laves-pharma.de

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