What is the difference between Colibiogen® and Synerga®, anyway?

Colibiogen® oral and Synerga® are identical in terms of concentration and active ingredient: They contain the highly purified metabolites of Escherichia coli strain Laves. However, Synerga® is free of any aroma additives and preservatives and therefore particularly suitable for patients with allergic problems (citrus fruits) and sensitive patients, while Colibiogen® additionally contains natural orange flavour and a preserving agent.

Colibiogen® Kinder is adjusted in terms of concentration to the juvenile organism and contains slightly more than half of the active ingredient in Colibiogen® oral. It contains no alcohol, but natural orange flavour to improve the taste.

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Can I give my child Synerga®?

Synerga® contains only 4.8 % alcohol. For a child, you would have to approximately halve the dose, so give half a teaspoon. You can dilute this with water, tea, etc.

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I have regularly problems when I have to take antibiotics. Can I take Colibiogen® simultaneously with the antibiotic?

Yes: Since it contains only metabolic products of the E. coli strain Laves and not live micro-organisms, co-administration with antibiotics poses no problem and is even recommended. By administration of antibiotics, the protective intestinal flora is also impaired. Together with the infection this often causes increased permeability of the intestine. Colibiogen® helps to close these gaps.

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I suffer from lactose intolerance. My doctor has prescribed Synerga® for me. But now I've read that it does contain lactose. Why should I use it nevertheless?

We know that some patients suffer from lactose intolerance and this appears contrary to the ingredient lactose in Synerga® and Colibiogen® Kinder, since Synerga® or Colibiogen® Kinder are also used for the treatment of lactose intolerance on the basis of a damaged intestinal mucosa.

Lactose is used to stabilize Synerga® and Colibiogen® Kinder because we do not use any preservatives (with the exception of very small amounts of alcohol – 4.8 %). This not least out of consideration for allergy patients, for whom otherwise even more problems would arise.

In lactase deficiency (primary = congenital, secondary = obtained in coeliac disease, small bowel conditions, etc.), the amount of lactase in the intestine is reduced. That means that a certain amount of lactose can be tolerated without any problems. The tolerable amount of lactose varies from person to person and depends on the respective health or integrity of the intestinal mucosa. In a low-lactose diet, at most 8 – 10 g are recommended, whereas in a lactose-free diet it should not be more than up to one gram per day.

If the ingested amount of lactose exceeds the amount that can be degraded by the enzyme lactase, there may be problems, because then undigested lactose may be carried over into the large intestine where it is split by the colonic bacteria into carbon dioxide, hydrogen, and lactic acid. These substances lead to the typical symptoms such as diarrhoea and increased bowel activity with flatulence.
Most patients who are treated with Synerga® / Colibiogen® Kinder and suffer from lactose intolerance will tolerate this without any problems, since on the one hand the amount of lactose is very low – 0.8 g / 5 ml Synerga® / Colibiogen® Kinder – and on the other  the mucous membrane is regenerated by Synerga® / Colibiogen® (a defective mucosa with an increased permeability is usually the cause of lactose intolerance, and thus by mucosal regeneration the lactose intolerance can be treated).

If the lactose intolerance is so pronounced that not even minute amounts of lactose are tolerated, please ask your doctor or pharmacist.

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I am diabetic and would like to know how many carbohydrate exchange units I have to consider when taking Colibiogen® / Synerga®!

The amount is negligible: 1 teaspoon (5 ml) contains only 0.07 carbohydrate exchange units!

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I suffer from coeliac disease. Can I take Colibiogen® / Synerga®?

Yes, because neither product contains gluten.

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My stool examination revealed an alleged overgrowth. Now I am supposed to take Colibiogen®, even though I have too many E. coli in the stool. Is that correct?

That is quite possible. There are many strains of Escherichia coli, of which a number are even patho-genic. They weaken your immune system and can cause illness. Colibiogen® contains no bacteria, but only the metabolic products of a specific E. coli strain, the strain Laves. This is not pathogenic, but on the contrary produces substances that can help an inflamed intestinal mucosa to regenerate.

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